Left Ventricular Hypertrophy: An allometric comparative analysis of different ECG markers

نویسندگان

  • M P Bonomini
  • MP Bonomini
  • F Ingallina
  • V Barone
چکیده

Allometry, in general biology, measures the relative growth of a part in relation to the whole living organism. Left ventricular hypertrophy (LVH) is the heart adaptation to excessive load (systolic or diastolic). The increase in left ventricular mass leads to an increase in the electrocardiographic voltages. Based on clinical data, we compared the allometric behavior of three different ECG markers of LVH. To do this, the allometric fit AECG = δ + β (VM) relating left ventricular mass (estimated from ecocardiographic data) and ECG amplitudes (expressed as the Cornell-Voltage, Sokolow and the ECG overall voltage indexes) were compared. Besides, sensitivity and specifity for each index were analyzed. The more sensitive the ECG criteria, the better the allometric fit. In conclusion: The allometric paradigm should be regarded as the way to design new and more sensitive ECG-based LVH markers.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Detection of Cardiac Hypertrophy by RVM and SVM Algorithms

The meaning of the hypertropy word is the increasing size.Heart hypertropy is symptoms of increase the thickness of the heart muscle that the left ventricular hypertrophy of them is the most common.The causes of hypertrophy heart disease are high blood pressure , aortic valve stenosis and sport activities respectively. Assessment of that by using ECG signal analysis is essential Because the ris...

متن کامل

Electrocardiographic left ventricular hypertrophy is not associated with increased in-hospital adverse events in patients experiencing first non-ST segment elevation myocardial infarction: A single center study

Background: There is conflicting data about prognostic implication of electrocardiographic (ECG) left ventricular hypertrophy (LVH) in patients with first non- ST-segment elevation myocardial infarction (NSTEMI). We aimed to examine the association of left ventricular hypertrophy (LVH) on admission electrocardiogram with adverse outcomes in patients with NSTEMI. Methods: In the present study, ...

متن کامل

Change of Body Surface Electrocardiogram is Linked to Left Ventricular Geometric Alteration from Normal, Pre-Hypertension to Hypertension: Comparison of NT-ProBNP and hs-CRP in Determining Ventricular Remodeling

Background: The presence of echocardiographic left ventricular remodeling and hypertrophy, a potential surrogate of pathophysiology intermediate between hypertension and heart failure, has been strongly linked to increased cardiovascular events. Electrocardiography (ECG) data regarding such a continuous change in pre-hypertension and hypertension subjects and their comparison with biomarkers ar...

متن کامل

Modulation of ECG Alterations and Cardiac Hypertrophy by Fenofibrate in Isoproterenol Induced Heart Failure

The present study was designed to evaluate the cardioprotective effect of fenofibrate against isoproterenol (ISO) induced heart failure (HF) in rats by studying cardiac injury markers, left ventricular hypertrophy and electrocardiographic changes. Rat model of HF was induced by ISO administration (85 mg/kg, s.c.) at an interval of 24h on 0 and 1st day. Fifteen days post ISO injection, rats show...

متن کامل

Effect of growth on variability of left ventricular mass: assessment of allometric signals in adults and children and their capacity to predict cardiovascular risk.

OBJECTIVES We sought to determine whether growth influences the relation between left ventricular mass and body size and whether use of different body size indexes affects the ability of ventricular mass to predict complications of hypertension. BACKGROUND Allometric (or growth) signals between left ventricular mass and height have recently been reported to improve previous approaches for nor...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2011